Prostate Apoptosis Response 4 (Par-4), a Novel Substrate of Caspase-3 during Apoptosis Activation

Prostate apoptosis response 4 (Par-4) is a ubiquitously expressed proapoptotic tumor suppressor protein. Here, we show for the first time, that Par-4 is a novel substrate of caspase-3 during apoptosis. We found that Par-4 is cleaved during cisplatin-induced apoptosis in human normal and cancer cell...

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Main Authors: Chaudhry, Parvesh, Singh, Mohan, Parent, Sophie, Asselin, Eric
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272980/
https://ncbi.nlm.nih.gov/pubmed/22184067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06321-11
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