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Parasporin-2 from a New Bacillus thuringiensis 4R2 Strain Induces Caspases Activation and Apoptosis in Human Cancer Cells

In previous studies, parasporin-2Aa1, originally isolated from Bacillus thuringiensis strain A1547, was shown to be cytotoxic against specific human cancer cells but the mechanisms of action were not studied. In the present study, we found that proteinase K activated parasporin-2Aa1 protein isolated...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Brasseur, Kevin, Auger, Pascal, Asselin, Eric, Parent, Sophie, Côté, Jean-Charles, Sirois, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532506/
https://ncbi.nlm.nih.gov/pubmed/26263002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135106
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