Parasporin-2 from a New Bacillus thuringiensis 4R2 Strain Induces Caspases Activation and Apoptosis in Human Cancer Cells

In previous studies, parasporin-2Aa1, originally isolated from Bacillus thuringiensis strain A1547, was shown to be cytotoxic against specific human cancer cells but the mechanisms of action were not studied. In the present study, we found that proteinase K activated parasporin-2Aa1 protein isolated...

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Publicat a:PLoS One
Autors principals: Brasseur, Kevin, Auger, Pascal, Asselin, Eric, Parent, Sophie, Côté, Jean-Charles, Sirois, Marc
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532506/
https://ncbi.nlm.nih.gov/pubmed/26263002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135106
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