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Extended Safety and Efficacy Studies of the Attenuated Brucella Vaccine Candidates 16MΔvjbR and S19ΔvjbR in the Immunocompromised IRF-1(−/−) Mouse Model

The global distribution of brucellosis and high incidence in certain areas of the world warrant the development of a safer and efficacious vaccine. For the past 10 years, we have focused our attention on the development of a safer, but still highly protective, live attenuated vaccine for human and a...

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Главные авторы: Arenas-Gamboa, A. M., Rice-Ficht, A. C., Fan, Y., Kahl-McDonagh, M. M., Ficht, T. A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272933/
https://ncbi.nlm.nih.gov/pubmed/22169089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05321-11
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