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The Brucella abortus S19 ΔvjbR Live Vaccine Candidate Is Safer than S19 and Confers Protection against Wild-Type Challenge in BALB/c Mice When Delivered in a Sustained-Release Vehicle

Brucellosis is an important zoonotic disease of nearly worldwide distribution. Despite the availability of live vaccine strains for bovine (S19, RB51) and small ruminants (Rev-1), these vaccines have several drawbacks, including residual virulence for animals and humans. Safe and efficacious immuniz...

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Detalhes bibliográficos
Main Authors: Arenas-Gamboa, A. M., Ficht, T. A., Kahl-McDonagh, M. M., Gomez, G., Rice-Ficht, A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632017/
https://ncbi.nlm.nih.gov/pubmed/19047401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01017-08
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