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Improving TCR Gene Therapy for Treatment of Haematological Malignancies

Adoptive immunotherapy using TCR gene modified T cells may allow separation of beneficial Graft versus tumour responses from harmful GvHD. Improvements to this include methods to generate high avidity or high affinity TCR, improvements in vector design and reduction in mispairing. Following adoptive...

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Bibliografische gegevens
Hoofdauteurs: Nicholson, Emma, Ghorashian, Sara, Stauss, Hans
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272793/
https://ncbi.nlm.nih.gov/pubmed/22319532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/404081
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