ATP11c is critical for phosphatidylserine internalization and B lymphocyte differentiation

Subcompartments of the plasma membrane are believed to be critical for lymphocyte responses but few genetic tools exist to test their function. Here we describe a new X-linked B cell deficiency syndrome in mice caused by mutations in Atp11c, a member of the P4 ATPase family thought to serve as flipp...

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Autors principals: Yabas, Mehmet, Teh, Charis E., Frankenreiter, Sandra, Lal, Dennis, Roots, Carla M., Whittle, Belinda, Andrews, Daniel T., Zhang, Yafei, Teoh, Narci C., Sprent, Jonathan, Tze, Lina E., Kucharska, Edyta M., Kofler, Jennifer, Farell, Geoffrey C., Bröer, Stefan, Goodnow, Christopher C., Enders, Anselm
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272780/
https://ncbi.nlm.nih.gov/pubmed/21423173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2011
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