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Head swivel on the ribosome facilitates translocation via intra-subunit tRNA hybrid sites

The elongation cycle of protein synthesis involves the delivery of aminoacyl-tRNAs to the A-site of the ribosome, followed by peptide-bond formation and translocation of the tRNAs through the ribosome to reopen the A-site(1,2). The translocation reaction is catalyzed by elongation factor G (EF-G) in...

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Bibliografiske detaljer
Main Authors: Ratje, Andreas H., Loerke, Justus, Mikolajka, Aleksandra, Brünner, Matthias, Hildebrand, Peter W., Starosta, Agata L., Dönhöfer, Alexandra, Connell, Sean R., Fucini, Paola, Mielke, Thorsten, Whitford, Paul C., Onuchic, Jose’ N, Yu, Yanan, Sanbonmatsu, Karissa Y., Hartmann, Roland K., Penczek, Pawel A., Wilson, Daniel N., Spahn, Christian M.T.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272701/
https://ncbi.nlm.nih.gov/pubmed/21124459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09547
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