Butylanilinouracil: a selective inhibitor of HeLa cell DNA synthesis and HeLa cell DNA polymerase alpha.

A series of 6-anilinouracils, dGTP analogues which selectively inhibit specific bacterial DNA polymerases, were examined for their capacity to inhibit purified DNA polymerases from HeLa cells. The p-n-butyl derivative (BuAU) was found to inhibit DNA polymerase alpha with a Ki of approximately 60 mic...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Wright, G E, Baril, E F, Brown, N C
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1980
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327245/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6153466/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/8.1.99
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