Characterization of a R plasmid-associated, trimethoprim-resistant dihydrofolate reductase and determination of the nucleotide sequence of the reductase gene.
The trimethoprim-resistant dihydrofolate reductase associated with the R plasmid R388 was isolated from strains that over-produce the enzyme. It was purified to apparent homogeneity by affinity chromatography and two consecutive gel filtration steps under native and denaturing conditions. The purifi...
Сохранить в:
| Опубликовано в:: | Nucleic Acids Res |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1981
|
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6261228/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/9.3.697 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
|