Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: Understanding the aging and cancer connection

Increasing chronological age is the most significant risk factor for cancer. Recently, we proposed a new paradigm for understanding the role of the aging and the tumor microenvironment in cancer onset. In this model, cancer cells induce oxidative stress in adjacent stromal fibroblasts. This, in turn...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Balliet, Renee M, Capparelli, Claudia, Guido, Carmela, Pestell, Timothy G, Martinez-Outschoorn, Ubaldo E, Lin, Zhao, Whitaker-Menezes, Diana, Chiavarina, Barbara, Pestell, Richard G, Howell, Anthony, Sotgia, Federica, Lisanti, Michael P
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Landes Bioscience 2011
विषय:
Report
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272288/
https://ncbi.nlm.nih.gov/pubmed/22129993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.23.18254
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