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Gamete Recognition in Mice Depends on the Cleavage Status of an Egg’s Zona Pellucida Protein

At fertilization, mouse sperm bind to the zona pellucida (which consists of glycoproteins ZP1, ZP2, and ZP3) that surrounds eggs. A ZP2 cleavage model of gamete recognition requires intact ZP2, and a glycan release model postulates that zona glycans are ligands for sperm. These two models were teste...

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Detalles Bibliográficos
Main Authors: Gahlay, Gagandeep, Gauthier, Lyn, Baibakov, Boris, Epifano, Olga, Dean, Jurrien
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272265/
https://ncbi.nlm.nih.gov/pubmed/20616279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1188178
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