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Distinct p53 genomic binding patterns in normal and cancer-derived human cells

Here, we report genome-wide analysis of the tumor suppressor p53 binding sites in normal human cells. 743 high-confidence ChIP-seq peaks representing putative genomic binding sites were identified in normal IMR90 fibroblasts using a reference chromatin sample. More than 40% were located within 2 kb...

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Bibliografiset tiedot
Päätekijät: Botcheva, Krassimira, McCorkle, Sean R, McCombie, WR, Dunn, John J, Anderson, Carl W
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2011
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272258/
https://ncbi.nlm.nih.gov/pubmed/22127205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.24.18383
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