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Differential binding of Escherichia coli McrA protein to DNA sequences that contain the dinucleotide m5CpG
The Escherichia coli McrA protein, a putative C(5)-methylcytosine/C(5)-hydroxyl methylcytosine-specific nuclease, binds DNA with symmetrically methylated HpaII sequences (Cm5CGG), but its precise recognition sequence remains undefined. To determine McrA’s binding specificity, we cloned and expressed...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847215/ https://ncbi.nlm.nih.gov/pubmed/20015968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1120 |
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