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p53 binding to human genome: crowd control navigation in chromatin context
p53 is the most studied human protein because of its role in maintaining genomic stability. Binding to genomic targets is essential for transcription-dependent p53 tumor suppression, but how p53 selects targets remains unclear. Here, the impact of chromatin context on p53 genome-wide binding and tar...
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| Veröffentlicht in: | Front Genet |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4273661/ https://ncbi.nlm.nih.gov/pubmed/25566329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00447 |
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