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Dynein achieves processive motion using both stochastic and coordinated stepping
Processivity, the ability of single molecules to move continuously along a track, is a fundamental requirement of cargo-transporting molecular motors. Here, we investigate how cytoplasmic dynein, a homodimeric, microtubule-based motor, achieves processive motion. To do this we developed a versatile...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272163/ https://ncbi.nlm.nih.gov/pubmed/22231401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2205 |
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