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The Winch Model Can Explain both Coordinated and Uncoordinated Stepping of Cytoplasmic Dynein

Cytoplasmic dynein moves processively along microtubules, but the mechanism of how its heads use the energy from ATP hydrolysis, coupled to a linker swing, to achieve directed motion, is still unclear. In this article, we present a theoretical model based on the winch mechanism in which the principa...

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Bibliografski detalji
Glavni autori: Šarlah, Andreja, Vilfan, Andrej
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129484/
https://ncbi.nlm.nih.gov/pubmed/25099805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.06.022
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