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The Winch Model Can Explain both Coordinated and Uncoordinated Stepping of Cytoplasmic Dynein
Cytoplasmic dynein moves processively along microtubules, but the mechanism of how its heads use the energy from ATP hydrolysis, coupled to a linker swing, to achieve directed motion, is still unclear. In this article, we present a theoretical model based on the winch mechanism in which the principa...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4129484/ https://ncbi.nlm.nih.gov/pubmed/25099805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.06.022 |
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