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Reconstitution of dynein transport to the microtubule plus end by kinesin

Cytoplasmic dynein powers intracellular movement of cargo toward the microtubule minus end. The first step in a variety of dynein transport events is the targeting of dynein to the dynamic microtubule plus end, but the molecular mechanism underlying this spatial regulation is not understood. Here, w...

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Autori principali: Roberts, Anthony J, Goodman, Brian S, Reck-Peterson, Samara L
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046564/
https://ncbi.nlm.nih.gov/pubmed/24916158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02641
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