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Formation of P450•P450 Complexes and Their Effect on P450 Function

Cytochromes P450 (P450) are membrane-bound enzymes that catalyze the monooxygenation of a diverse array of xenobiotic and endogenous compounds. The P450s responsible for foreign compound metabolism generally are localized in the endoplasmic reticulum of the liver, lung and small intestine. P450 enzy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Reed, James R., Backes, Wayne L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272114/
https://ncbi.nlm.nih.gov/pubmed/22155419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2011.11.009
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