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Physical Studies of P450–P450 Interactions: Predicting Quaternary Structures of P450 Complexes in Membranes from Their X-ray Crystal Structures

Cytochrome P450 enzymes, which catalyze oxygenation reactions of both exogenous and endogenous chemicals, are membrane bound proteins that require interaction with their redox partners in order to function. Those responsible for drug and foreign compound metabolism are localized primarily in the end...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Reed, James R., Backes, Wayne L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5276844/
https://ncbi.nlm.nih.gov/pubmed/28194112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00028
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