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Hybrid modeling and simulation of stochastic effects on progression through the eukaryotic cell cycle

The eukaryotic cell cycle is regulated by a complicated chemical reaction network. Although many deterministic models have been proposed, stochastic models are desired to capture noise in the cell resulting from low numbers of critical species. However, converting a deterministic model into one that...

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Main Authors: Liu, Zhen, Pu, Yang, Li, Fei, Shaffer, Clifford A., Hoops, Stefan, Tyson, John J., Cao, Yang
格式: Artigo
語言:Inglês
出版: American Institute of Physics 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272065/
https://ncbi.nlm.nih.gov/pubmed/22280742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3677190
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