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Conditional targeting of E-cadherin in skin: Insights into hyperproliferative and degenerative responses

Loss of E-cadherin has been associated with human cancers, and yet in the early mouse embryo and the lactating mammary gland, the E-cadherin null state results in tissue dysfunction and cell death. Here we targeted loss of E-cadherin in skin epithelium. The epidermal basal layer responded by elevati...

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Detalhes bibliográficos
Principais autores: Tinkle, Christopher L., Lechler, Terry, Pasolli, H. Amalia, Fuchs, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC327185/
https://ncbi.nlm.nih.gov/pubmed/14704278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307437100
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