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The presenilins turned inside out: Implications for their structures and functions
The presenilin (PS) proteins are polytopic integral membrane proteins that are critically involved in the development of Alzheimer's disease. The topography of the PS molecule in the endoplasmic reticulum membrane is widely accepted as exhibiting eight-hydrophobic-transmembrane (8-TM) helices....
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC327150/ https://ncbi.nlm.nih.gov/pubmed/14732691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307290101 |
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