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The presenilins turned inside out: Implications for their structures and functions
The presenilin (PS) proteins are polytopic integral membrane proteins that are critically involved in the development of Alzheimer's disease. The topography of the PS molecule in the endoplasmic reticulum membrane is widely accepted as exhibiting eight-hydrophobic-transmembrane (8-TM) helices....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC327150/ https://ncbi.nlm.nih.gov/pubmed/14732691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307290101 |
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