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The presenilins turned inside out: Implications for their structures and functions

The presenilin (PS) proteins are polytopic integral membrane proteins that are critically involved in the development of Alzheimer's disease. The topography of the PS molecule in the endoplasmic reticulum membrane is widely accepted as exhibiting eight-hydrophobic-transmembrane (8-TM) helices....

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Dewji, Nazneen N., Valdez, Dante, Singer, S. J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327150/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14732691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307290101
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