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On the spurious endoproteolytic processing of the presenilin proteins in cultured cells and tissues

It has been widely reported that the presenilin proteins PS-1 and PS-2 in extracts derived from a variety of cultured cells and from tissues are fragmented extensively by endoproteolytic processing events. It generally has been presumed that this endoproteolysis is a physiologically normal intracell...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Dewji, Nazneen N., Do, Chau, Singer, S. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1997
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28427/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9391147/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.25.14031
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