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Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites
Analysis of the human genome sequence has identified ≈25,000–30,000 protein-coding genes, but little is known about how most of these are regulated. Mapping DNase I hypersensitive (HS) sites has traditionally represented the gold-standard experimental method for identifying regulatory elements, but...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC327130/ https://ncbi.nlm.nih.gov/pubmed/14732688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307540100 |
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