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Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1
The mitotic spindle checkpoint protein Bub1 has been found to be mutated at low frequency in certain human cancers characterized by aneuploidy. Simian virus 40 large T antigen efficiently immortalizes rodent cells and occasionally transforms them to tumorigenicity. T antigen can also cause genomic i...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC327122/ https://ncbi.nlm.nih.gov/pubmed/14732683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308006100 |
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