Quinoline Derivatives Are Therapeutic Candidates for Transmissible Spongiform Encephalopathies
We previously reported that quinacrine inhibited the formation of an abnormal prion protein (PrPres), a key molecule in the pathogenesis of transmissible spongiform encephalopathy, or prion disease, in scrapie-infected neuroblastoma cells. To elucidate the structural aspects of its inhibiting action...
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| Veröffentlicht in: | J Virol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2004
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14722283/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.3.1281-1288.2004 |
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