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Quinoline Derivatives Are Therapeutic Candidates for Transmissible Spongiform Encephalopathies
We previously reported that quinacrine inhibited the formation of an abnormal prion protein (PrPres), a key molecule in the pathogenesis of transmissible spongiform encephalopathy, or prion disease, in scrapie-infected neuroblastoma cells. To elucidate the structural aspects of its inhibiting action...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology
2004
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC327112/ https://ncbi.nlm.nih.gov/pubmed/14722283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.3.1281-1288.2004 |
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