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Parallel Evolution under Chemotherapy Pressure in 29 Breast Cancer Cell Lines Results in Dissimilar Mechanisms of Resistance

BACKGROUND: Developing chemotherapy resistant cell lines can help to identify markers of resistance. Instead of using a panel of highly heterogeneous cell lines, we assumed that truly robust and convergent pattern of resistance can be identified in multiple parallel engineered derivatives of only a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tegze, Bálint, Szállási, Zoltán, Haltrich, Irén, Pénzváltó, Zsófia, Tóth, Zsuzsa, Likó, István, Győrffy, Balázs
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271089/
https://ncbi.nlm.nih.gov/pubmed/22319589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030804
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