Absence of HIV-1 Evolution in the Gut-Associated Lymphoid Tissue from Patients on Combination Antiviral Therapy Initiated during Primary Infection

Mucosal mononuclear (MMC) CCR5+CD4+ T cells of the gastrointestinal (GI) tract are selectively infected and depleted during acute HIV-1 infection. Despite early initiation of combination antiretroviral therapy (cART), gut-associated lymphoid tissue (GALT) CD4+ T cell depletion and activation persist...

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Main Authors: Evering, Teresa H., Mehandru, Saurabh, Racz, Paul, Tenner-Racz, Klara, Poles, Michael A., Figueroa, Amir, Mohri, Hiroshi, Markowitz, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271083/
https://ncbi.nlm.nih.gov/pubmed/22319447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002506
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