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Primary HIV-1 Infection Is Associated with Preferential Depletion of CD4(+) T Lymphocytes from Effector Sites in the Gastrointestinal Tract

Given its population of CCR5-expressing, immunologically activated CD4(+) T cells, the gastrointestinal (GI) mucosa is uniquely susceptible to human immunodeficiency virus (HIV)-1 infection. We undertook this study to assess whether a preferential depletion of mucosal CD4(+) T cells would be observe...

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Detalhes bibliográficos
Main Authors: Mehandru, Saurabh, Poles, Michael A., Tenner-Racz, Klara, Horowitz, Amir, Hurley, Arlene, Hogan, Christine, Boden, Daniel, Racz, Paul, Markowitz, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211967/
https://ncbi.nlm.nih.gov/pubmed/15365095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041196
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