Lack of Mucosal Immune Reconstitution during Prolonged Treatment of Acute and Early HIV-1 Infection

BACKGROUND: During acute and early HIV-1 infection (AEI), up to 60% of CD4(+) T cells in the lamina propria of the lower gastrointestinal (GI) tract are lost as early as 2–4 wk after infection. Reconstitution in the peripheral blood during therapy with highly active antiretroviral therapy (HAART) is...

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Main Authors: Mehandru, Saurabh, Poles, Michael A, Tenner-Racz, Klara, Jean-Pierre, Patrick, Manuelli, Victoria, Lopez, Peter, Shet, Anita, Low, Andrea, Mohri, Hiroshi, Boden, Daniel, Racz, Paul, Markowitz, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762085/
https://ncbi.nlm.nih.gov/pubmed/17147468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030484
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