Raf1 Is a DCAF for the Rik1 DDB1-Like Protein and Has Separable Roles in siRNA Generation and Chromatin Modification

Non-coding transcription can trigger histone post-translational modifications forming specialized chromatin. In fission yeast, heterochromatin formation requires RNAi and the histone H3K9 methyltransferase complex CLRC, composed of Clr4, Raf1, Raf2, Cul4, and Rik1. CLRC mediates H3K9 methylation and...

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Main Authors: Buscaino, Alessia, White, Sharon A., Houston, Douglas R., Lejeune, Erwan, Simmer, Femke, de Lima Alves, Flavia, Diyora, Piyush T., Urano, Takeshi, Bayne, Elizabeth H., Rappsilber, Juri, Allshire, Robin C.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271066/
https://ncbi.nlm.nih.gov/pubmed/22319459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002499
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