Raf1 Is a DCAF for the Rik1 DDB1-Like Protein and Has Separable Roles in siRNA Generation and Chromatin Modification

Non-coding transcription can trigger histone post-translational modifications forming specialized chromatin. In fission yeast, heterochromatin formation requires RNAi and the histone H3K9 methyltransferase complex CLRC, composed of Clr4, Raf1, Raf2, Cul4, and Rik1. CLRC mediates H3K9 methylation and...

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Autori principali: Buscaino, Alessia, White, Sharon A., Houston, Douglas R., Lejeune, Erwan, Simmer, Femke, de Lima Alves, Flavia, Diyora, Piyush T., Urano, Takeshi, Bayne, Elizabeth H., Rappsilber, Juri, Allshire, Robin C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271066/
https://ncbi.nlm.nih.gov/pubmed/22319459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002499
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