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Hemostatic Safety and Antithrombotic Efficacy of Moderate Platelet Count Reduction by Thrombopoietin Inhibition in Primates

Most heart attacks and strokes are caused by blood clots (thrombi) that block the vasculature. Since arterial thrombosis is a blood platelet-dependent disease, platelet inhibitors such as aspirin and clopidogrel are effective; however, they also impair platelet-dependent hemostasis, and can produce...

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Hlavní autoři: Tucker, Erik I., Marzec, Ulla M., Berny, Michelle A., Hurst, Sawan, Bunting, Stuart, McCarty, Owen J.T., Gruber, András, Hanson, Stephen R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271054/
https://ncbi.nlm.nih.gov/pubmed/20574069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000697
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