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Hemostatic Safety and Antithrombotic Efficacy of Moderate Platelet Count Reduction by Thrombopoietin Inhibition in Primates

Most heart attacks and strokes are caused by blood clots (thrombi) that block the vasculature. Since arterial thrombosis is a blood platelet-dependent disease, platelet inhibitors such as aspirin and clopidogrel are effective; however, they also impair platelet-dependent hemostasis, and can produce...

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Bibliografiska uppgifter
Huvudupphovsmän: Tucker, Erik I., Marzec, Ulla M., Berny, Michelle A., Hurst, Sawan, Bunting, Stuart, McCarty, Owen J.T., Gruber, András, Hanson, Stephen R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271054/
https://ncbi.nlm.nih.gov/pubmed/20574069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000697
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