Insights into High Affinity Small Ubiquitin-like Modifier (SUMO) Recognition by SUMO-interacting Motifs (SIMs) Revealed by a Combination of NMR and Peptide Array Analysis

The small ubiquitin-like modifiers (SUMOs) regulate many essential cellular functions. Only one type of SUMO-interacting motif (SIM) has been identified that can extend the β-sheet of SUMO as either a parallel or an antiparallel strand. The molecular determinants of the bound orientation and paralog...

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Autori principali: Namanja, Andrew T., Li, Yi-Jia, Su, Yang, Wong, Steven, Lu, Jingjun, Colson, Loren T., Wu, Chenggang, Li, Shawn S. C., Chen, Yuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Molecular Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270977/
https://ncbi.nlm.nih.gov/pubmed/22147707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.293118
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