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The C Terminus of Formin FMNL3 Accelerates Actin Polymerization and Contains a WH2 Domain-like Sequence That Binds Both Monomers and Filament Barbed Ends

Formin proteins are actin assembly factors that accelerate filament nucleation then remain on the elongating barbed end and modulate filament elongation. The formin homology 2 (FH2) domain is central to these activities, but recent work has suggested that additional sequences enhance FH2 domain func...

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Detalles Bibliográficos
Main Authors: Heimsath, Ernest G., Higgs, Henry N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270965/
https://ncbi.nlm.nih.gov/pubmed/22094460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.312207
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