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Structure of the FMNL3 FH2/actin complex provides insight into formin-mediated actin nucleation and elongation

Formins are actin assembly factors that act in a variety of actin-based processes. The conserved formin homology 2 (FH2) domain promotes filament nucleation and influences elongation via interaction with the barbed end. FMNL3 is a formin that induces assembly of filopodia but whose FH2 domain is a p...

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Bibliografische gegevens
Hoofdauteurs: Thompson, Morgan E., Heimsath, Ernest G., Gauvin, Timothy J., Higgs, Henry N., Kull, F. Jon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876896/
https://ncbi.nlm.nih.gov/pubmed/23222643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2462
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