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Hypokinesia and Reduced Dopamine Levels in Zebrafish Lacking β- and γ1-Synucleins
α-Synuclein is strongly implicated in the pathogenesis of Parkinson disease. However, the normal functions of synucleins and how these relate to disease pathogenesis are uncertain. We characterized endogenous zebrafish synucleins in order to develop tractable models to elucidate the physiological ro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3270954/ https://ncbi.nlm.nih.gov/pubmed/22128150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308312 |
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