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PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways
The paraoxonase (PON) group of enzymes, composed of PON1, PON2, and PON3, play an important role in decreasing oxidative stress by degrading lipid peroxides. PON1 synthesis is upregulated by PPAR. Several pharmacological compounds (acting as antioxidants and, hence, atheroprotective) stimulate both...
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Hoofdauteurs: | , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Hindawi Publishing Corporation
2012
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3270466/ https://ncbi.nlm.nih.gov/pubmed/22315585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/616371 |
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