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PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways

The paraoxonase (PON) group of enzymes, composed of PON1, PON2, and PON3, play an important role in decreasing oxidative stress by degrading lipid peroxides. PON1 synthesis is upregulated by PPAR. Several pharmacological compounds (acting as antioxidants and, hence, atheroprotective) stimulate both...

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Bibliografische gegevens
Hoofdauteurs: Camps, Jordi, García-Heredia, Anabel, Rull, Anna, Alonso-Villaverde, Carlos, Aragonès, Gerard, Beltrán-Debón, Raúl, Rodríguez-Gallego, Esther, Joven, Jorge
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270466/
https://ncbi.nlm.nih.gov/pubmed/22315585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/616371
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