PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways

The paraoxonase (PON) group of enzymes, composed of PON1, PON2, and PON3, play an important role in decreasing oxidative stress by degrading lipid peroxides. PON1 synthesis is upregulated by PPAR. Several pharmacological compounds (acting as antioxidants and, hence, atheroprotective) stimulate both...

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Detalhes bibliográficos
Main Authors: Camps, Jordi, García-Heredia, Anabel, Rull, Anna, Alonso-Villaverde, Carlos, Aragonès, Gerard, Beltrán-Debón, Raúl, Rodríguez-Gallego, Esther, Joven, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270466/
https://ncbi.nlm.nih.gov/pubmed/22315585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/616371
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