Sirolimus Enhances Cyclosporine A-Induced Cytotoxicity in Human Renal Glomerular Mesangial Cells

End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms underlying disease progression are not fully elucidated. This work addressed nephrotoxicity induced by the immunosuppressive agents' cyclosporine A (CsA) and sirolimus (SRL). Nephrotoxicity is the maj...

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Bibliografiske detaljer
Main Authors: O'Connell, Séin, Slattery, Craig, Ryan, Michael P., McMorrow, Tara
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270447/
https://ncbi.nlm.nih.gov/pubmed/22315658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/980910
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