Sirolimus Enhances Cyclosporine A-Induced Cytotoxicity in Human Renal Glomerular Mesangial Cells

End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms underlying disease progression are not fully elucidated. This work addressed nephrotoxicity induced by the immunosuppressive agents' cyclosporine A (CsA) and sirolimus (SRL). Nephrotoxicity is the maj...

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Autores principales: O'Connell, Séin, Slattery, Craig, Ryan, Michael P., McMorrow, Tara
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270447/
https://ncbi.nlm.nih.gov/pubmed/22315658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/980910
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