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Sirolimus Enhances Cyclosporine A-Induced Cytotoxicity in Human Renal Glomerular Mesangial Cells

End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms underlying disease progression are not fully elucidated. This work addressed nephrotoxicity induced by the immunosuppressive agents' cyclosporine A (CsA) and sirolimus (SRL). Nephrotoxicity is the maj...

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Detalhes bibliográficos
Main Authors: O'Connell, Séin, Slattery, Craig, Ryan, Michael P., McMorrow, Tara
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270447/
https://ncbi.nlm.nih.gov/pubmed/22315658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/980910
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