Influence of Morphine on Pericyte-Endothelial Interaction: Implications for Antiangiogenic Therapy

Morphine stimulates tumor angiogenesis and cancer progression in mice. We examined if morphine influences endothelial-pericyte interaction via platelet-derived growth factor-BB (PDGF-BB) and PDGF receptor-β (PDGFR-β). Clinically relevant doses of morphine stimulated PDGF-BB secretion from human umbi...

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Detalhes bibliográficos
Main Authors: Luk, Kathryn, Boatman, Sonja, Johnson, Katherine N., Dudek, Olivia A., Ristau, Natalie, Vang, Derek, Nguyen, Julia, Gupta, Kalpna
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270445/
https://ncbi.nlm.nih.gov/pubmed/22315595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/458385
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