Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations

The crystal structures of acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis (Mtb) and Corynebacterium ammoniagenes determined at pH 5.3 and pH 6.5, respectively, are reported. Comparison of the Mtb apo-AcpS structure with the recently reported structure of the Mtb AcpS–ADP complex...

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Bibliografiska uppgifter
Huvudupphovsmän: Gokulan, Kuppan, Aggarwal, Anup, Shipman, Lance, Besra, Gurdyal S., Sacchettini, James C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: International Union of Crystallography 2011
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270384/
https://ncbi.nlm.nih.gov/pubmed/21697604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444911020221
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