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Mitogen- and Stress-Activated Kinase 1 (MSK1) Regulates Cigarette Smoke-Induced Histone Modifications on NF-κB-dependent Genes

Cigarette smoke (CS) causes sustained lung inflammation, which is an important event in the pathogenesis of chronic obstructive pulmonary disease (COPD). We have previously reported that IKKα (I kappaB kinase alpha) plays a key role in CS-induced pro-inflammatory gene transcription by chromatin modi...

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Detaylı Bibliyografya
Asıl Yazarlar: Sundar, Isaac K., Chung, Sangwoon, Hwang, Jae-woong, Lapek, John D., Bulger, Michael, Friedman, Alan E., Yao, Hongwei, Davie, James R., Rahman, Irfan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270039/
https://ncbi.nlm.nih.gov/pubmed/22312446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031378
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