Mitogen- and Stress-Activated Kinase 1 (MSK1) Regulates Cigarette Smoke-Induced Histone Modifications on NF-κB-dependent Genes

Cigarette smoke (CS) causes sustained lung inflammation, which is an important event in the pathogenesis of chronic obstructive pulmonary disease (COPD). We have previously reported that IKKα (I kappaB kinase alpha) plays a key role in CS-induced pro-inflammatory gene transcription by chromatin modi...

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Detalhes bibliográficos
Main Authors: Sundar, Isaac K., Chung, Sangwoon, Hwang, Jae-woong, Lapek, John D., Bulger, Michael, Friedman, Alan E., Yao, Hongwei, Davie, James R., Rahman, Irfan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270039/
https://ncbi.nlm.nih.gov/pubmed/22312446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031378
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