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Precise localisation of three intra-RNA cross-links in 23S RNA and one in 5S RNA, induced by treatment of Escherichia coli 50S ribosomal subunits with bis-(2-chloroethyl)-methylamine.

Treatment of E. coli 50S ribosomal subunits with low doses of bis-(2-chloroethyl)-methylamine ("nitrogen mustard") leads to formation of a number of intra-RNA and RNA-protein cross-links. After partial digestion of the cross-linked subunits with cobra venom nuclease, followed by destruction of the p...

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Pubblicato in:Nucleic Acids Res
Autori principali: Stiege, W, Zwieb, C, Brimacombe, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326999/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6818528/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/10.22.7211
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